Causes for increased Maternal Serum AFP During Pregnancy

Mnemonic: “Increased Maternal Serum Alpha Feto Protein”

Increased: Intestinal obstruction

Maternal: Multiple gestation/ Miscalculation of gestational age/ Myeloschisis

Serum: Spina bifida cystica

Alpha: Anencephaly/ Abdominal wall defect

Feto: Fetal death

Protein: Placental abruption

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